カテゴリー「thyroid cancer」
Title: MOLECULAR CYTOGENETIC STUDIESON CHILDHOOD THYROID TUMOURS FROM BELARUS
Author: H. Zitzelsberger, J. Smida, K. Salassidis, L. Heiber, M. Bauchinger
Reference: Zitzelsberger et al. / International journal of radiation medicine 1999, 34 (34): 1719
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Abstract: Since 1992, tissue specimens from 264 childhood thyroid tumours from Belarus were received by the Institute of Radiobiology at GSF. For control, tumour samples from Belarussian adults, papillary carcinomas without radiation history and secondary thyroid tumours developed after radiotherapy were also collected. Based on this tissue and cell culture collection, several molecular cytogenetic studies were carried out investigating aberrations in subgroups of these tumours at the chromosomal and molecular level. These studies include the quantification of chromosomal aberrations by FISH-painting (Lehmann L. et al., 1996), G-banding and breakpoint analyses of chromosomal aberrations (Lehmann L. et al., 1997; Zitzelsberger H. et al., in press), analyses of p53 mutations (Smida J. et al., 1997) and RET rearrangements (Smida J. et al., in press) and an expression profiling of activated tyrosine kinase genes. This presentation focuses on cytogenetic studies and the investigation of RET rearrangements
URL: http://www.physiciansofchernobyl.org.ua/magazine/PDFS/3-4_1999/3_3_99_61.pdf
Author: V.G. Bebeshko, D.A. Bazyka, A.Yu. Romanenko, K.M. Loganovsky
Reference: Journal of AMS of Ukraine, 2011
Abstract: Article by Ukraine’s leading experts. Comprehends aspects of radiation safety, health protection, ecology, neuropsychiatry, immunology etc. Full text available in Ukrainian on web.
URL: http://archive.nbuv.gov.ua/portal/chem_biol/jamn/2011_2/Bebeshko.pdf
Title: RETROSPECTIVE RECONSTRUCTION OF THE THYROID DOSES AFTER THE CHERNOBYL ACCIDENT
Author: G. Goulko
Reference: International journal of radiation medicine GSF-National Research Center for Environment and Health Institute for Radiation Protection, D-85764 Neuherberg, Germany
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Abstract: Thyroid cancer incidence in exposed children is increased in the most contaminated areas during last 5.8 years (Buglova E.E. et al., 1996; Ivannov V.K. et al., 1997; Goulko G. et al., 1998; Jacob P. et al., 1998). These results generally confirm first predictions about expected thyroid cancer rate made for the selected areas of Ukraine in 1991 (Likhtarev I.A. et al., 1993). During the time passed after the Chernobyl accident a lot of efforts were made in Ukraine, Belarus and Russia to improve thyroid dose estimates due to 131I (Pitkevich V.A. et al., 1993; Zvonova I.A., Balonov M.I., 1993; Likhtarev I.A. et al., 1994. 1996; Tsyb A.F. et al., 1994; Gavrilin Y. et al., 1996; Goulko G.M. et al., 1996, 1998; Drozdovitch V.V. et al., 1997). Increased interest to this problem initiated several epidemiological studies considering different groups of people exposed in childhood due to the Chernobyl accident.
URL: http://www.physiciansofchernobyl.org.ua/magazine/PDFS/3-4_1999/3_3_99_60.pdf
Redactor: A.M. Serdyuk, V.G. Bebeshko, D.A. Bazyka
Reference: Тернопіль: ТДМУ «Укрмедкнига» (Ternopil State Medical University), 2011
Abstract: A book redacted by some of the leading Ukrainian experts. For details please contact the Ternopil State Medical University. University’s homepage: http://www.tdmu.edu.te.ua/eng/general/index.php
Ukrainian title: Медичні наслідки Чорнобильської катастрофи 1986–2011
Title: THYROID CANCER AMONG THE BELARUSSIAN AND RUSSIAN POPULATION EXPOSED BY THE CHERNOBYL ACCIDENT
Author: P. Jacob
Reference: International journal of radiation medicine 1999, 3.4 (3.4): 7.10
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Abstract: A large increase of the thyroid cancer incidence among those who were children at the time of the accident was observed in Belarus and in Ukraine (Kazakov V.S. et al., 1992; Likhtarev I.A. et al., 1995). The increase in Belarus among those who were younger than 18 years at the time of the accident started in 1989 with a linear rise to about 140 cases per year in 1994 and then staying up to 1996 (the last date of published data) on a constant level (Buglova E. et al., 1997). A case-control study indicated a strong relationship between thyroid cancer and estimated radiation dose from the Chernobyl accident (Astakova L.N. et al., 1998). An aggregate study of the thyroid cancer after Chernobyl has shown the large potential of such studies for deriving quantitative information on the cancer risk due to 131I incorporation
URL: http://www.physiciansofchernobyl.org.ua/magazine/PDFS/3-4_1999/3_3_99_59.pdf
Author: T.P. Golivets, B.S. Kovalenko, I.V. Sukhoterin, D.V. Volkov
Reference: Журнал: Научные ведомости Белгородского государственного университета. Серия: Медицина. Фармация (Journal: Scientific register of the Belgorod State University. Series: Medicine. Farmacy, 2010
Doi: 616.43;616-008.9;616.39
Keywords: Belgorod region, malignant tumor
Abstract: Overview on the 25-year period from 1981 to 2005. Dynamics of morbidity is researched in different age groups of both sexes. In every age group, increase of thyroid cancer incidence is detected. It evidences again the already known features of thyroid oncopathology.
URL: http://cyberleninka.ru/article/n/zabolevaemost-rakom-schitovidnoy-zhelezy-naseleniya-belgorodskoy-oblasti-v-1981-2005-gg
Reference: Проблеми радіаційної медицини та радіобіології (Problems of Radiation Medicine and Radiobiology), 2007
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Title: The problem of thyroid cancer in Russia after the Chernobyl accident:evaluation of radiation risks, observation period 1991-2008
Author: Ivanov V.K., Tsyb A.F., Maksyutov M.A., Tumanov K.A., Chekin S.YU., Kascheev V.V., Korelo A.M., Vlasov O.K., Schukina N.V.
Reference: Journal “Radiation and Lisk” 2010, Vol.19 No.3
Keywords: Chernobyl accident, territory contaminated with radionuclides, Population, thyroid cancer, incidence of disease, crude incidence rate, standardized incidence ratio, excess relative risk
Abstract: Joint analysis of thyroid cancer incidence in Bryansk, Kaluga, Oryol and Tula oblasts from 1981 through 2008 was made for the first time. The average size of population of the oblasts in those years was 5.1 million people. According to data of the National Radiation and Epidemiological Registry 9120 thyroid cancer cases were detected for that period. Mean-rayon thyroid doses were used for the analysis. Affected rayons of Bryansk, Kaluga, Oryol and Tula oblasts were arranged into 4 groups in accordance with radiation dose:
URL: http://cyberleninka.ru/article/n/problema-raka-schitovidnoy-zhelezy-v-rossii-posle-avarii-na-chernobylskoy-aes-otsenka-radiatsionnyh-riskov-period-nablyudeniya-1991-2008
Author: V.K. Ivanov
Reference: Журнал: Радиация и риск (journal: Radiation and Risk), 2010
Abstract: Aims of the work:
- To approve the assessment work of radiation risks of thyroid cancer in people, living in contaminated territories by the Chernobyl accident, administered by the MRRC RAMS (National Radiation and Epidemiological Registry
- Take note of the main results of large-scale radiation epidemiological studies conducted in the years 1991-2008 on the population of Bryansk, Kaluga, Orel and Tula regions, according to which:
– A group of radiation risk for thyroid cancer should include children and adolescents (0-17 years at the time of the Chernobyl accident);
– No significant radiation risk of thyroid cancer among adult (at the time of the Chernobyl accident) population has been found…
URL: http://cyberleninka.ru/article/n/zaklyuchenie-rnkrz-po-dokladu-zabolevaemost-rakom-schitovidnoy-zhelezy-v-rossii-posle-avarii-na-chernobylskoy-aes-otsenka-radiatsionnyh