カテゴリー「obstetrics and gynecology」
Title: Risk of Radiation Exposure to Children and Their Mothers
Author: Petrova, A.
Reference: Encyclopedia of Environmental Health, Jan 2011
ISBN:9780444522726
Keywords: Children; Mothers; Radiation; Risk
Abstract: There is realistic concern about the impact of ionizing and nonionizing radiations on the health of children and their mothers. The magnitude and type of risks that are associated with radiation exposure to children and mothers must be determined to prevent the health consequences of such exposure. The developing organism is more sensitive to radiation and vulnerable to the development of radiation-induced pathology. Prenatal development, characterized by intensive cell proliferation, cell differentiation, and cell migration, is highly sensitive to radiation exposure. …Human epidemiological studies showed increased stillbirth trend, birth defects, thyroid cancer, and infant leukemia after the Chernobyl Nuclear Power accident in several European countries. …
URL: http://www.sciencedirect.com/science/article/pii/B9780444522726002129
Title: The intellectual development, mental and behavioural disorders in children from Belarus exposed in utero following the Chernobyl accident
Author: Igumnov, S / Drozdovitch, V
Reference: European Psychiatry, 15 (4), p.244-253, Jun 2000
doi: 10.1016/S0924-9338(00)00237-6
Keywords: education; emotional disorder; exposure; prenatal; social factors; specific learning ; thyroid dose
Abstract: The study examined psychological development in 250 children at the age of 6–7 and 10–12 years who had been exposed in the prenatal period at the time of the Chernobyl accident in 1986. These children were compared to a control group of 250 children of the same age from non- and slightly contaminated areas of Belarus. The examination included psychiatric examination and intellectual assessment as well as the estimation of thyroid exposure in utero. The mean value of thyroid doses from 131I 0.39 Gy was estimated for the prenatal exposed children….
URL: http://www.sciencedirect.com/science/article/pii/S0924933800002376
Title: The intellectual development, mental and behavioural disorders in children from Belarus exposed in utero following the Chernobyl accident
Author: Igumnov, S / Drozdovitch, V
Reference: European Psychiatry, 15 (4), p.244-253, Jun 2000
doi: 10.1016/S0924-9338(00)00237-6
Keywords: education; emotional disorder; exposure; prenatal; social factors; specific learning disabilities; thyroid dose
Abstract: The study examined psychological development in 250 children at the age of 6–7 and 10–12 years who had been exposed in the prenatal period at the time of the Chernobyl accident in 1986. These children were compared to a control group of 250 children of the same age from non- and slightly contaminated areas of Belarus. The examination included psychiatric examination and intellectual assessment as well as the estimation of thyroid exposure in utero. The mean value of thyroid doses from 131I 0.39 Gy was estimated for the prenatal exposed children….
URL: http://www.sciencedirect.com/science/article/pii/S0924933800002376
Title: Birth Defects Thyroid Cancer Chernobyl
Reference: [PDF-2MB]Oct 2007
Abstract: …Nord-England* * Cotterill SJ, Pearce MS, Parker L (2001) Eur J Cancer. 37(8):1020-1026 Diese zeitlichen und räumlichen Änderungen…in Kärnten (Österreich) * * Segovia IG et al. (2004) THYROID 14(4), 277-285 Die Inzidenz des papillären Schilddrüsenkrebs…
URL: http://www.helmholtz-muenchen.de/ibb/homepage/hagen.scherb/Birth%20Defects%20Thyroid%20Cancer%20Chernobyl.pdf
Title: Testicular steroidogenesis is not altered by 137 cesium Chernobyl fallout, following in utero or post-natal chronic exposure.
Author: Grignard, Elise; Guéguen, Yann; Grison, Stéphane; Dublineau, Isabelle; Gourmelon, Patrick; Souidi, Maâmar.
Reference: Comptes Rendus Biologies. May2010, Vol. 333 Issue 5, p416-423. 8p.
doi: 10.1016/j.crvi.2010.02.003.
Keywords: TESTIS — Physiology; CESIUM — Isotopes; STEROID hormones — Synthesis; CHERNOBYL Nuclear Accident, Chornobyl, Ukraine, 1986; GENE expression; CONTAMINATION (Technology); RATS as laboratory animals
Abstract: The testis is especially sensitive to pollutants, including radionuclides. Following the Chernobyl nuclear power plant accident, several of these radionuclides were emitted and spread in the environment. Subsequently, children presented some disruptions of the endocrine system. To determine whether these disruptions were due to 137 cesium (137Cs) exposure, the effects of chronic contamination with low doses of 137Cs in utero or from birth on testicular steroidogenesis in rats were studied. Contamination was continued for 9 months. No modification was observed in circulating level of hormones (17β-estradiol, testosterone, follicle-stimulating hormone, luteinizing hormone) following in utero or post-natal contamination. Expression of several genes involved in testicular steroidogenesis was affected (cyp19a1, fxr, sf-1), without modification of protein expression or activity. Our results suggest that growing organisms may be affected at the molecular level by 137Cs contamination at this post-accidental dose.
URL: http://www.sciencedirect.com/science/article/pii/S1631069110000466
