Title: Microsoft Word – 196.00.doc
Reference: American cancer society [PDF-175K]Jun 2012
Keywords:
Abstract: …risk of thyroid cancer in children because…For instance, thyroid cancer is several times…children living near Chernobyl, the site of a…than that around Chernobyl. A higher risk of thyroid cancer has not been proven…
URL: http://www.cancer.org/acs/groups/cid/documents/webcontent/003144-pdf.pdf
Title: Micronucleus frequency in Gomel (Belarus) children affected and not affected by thyroid cancer
Author: Zotti-Martelli, Laura / Migliore, Lucia / Panasiuk, Galina / Barale, Roberto
Reference: Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 440 (1), p.35-43, Mar 1999
doi: 10.1016/S1383-5718(99)00012-1
Keywords: Human lymphocyte micronucleus assay; Thyroid cancer; Chernobyl accident; Ionizing radiation
Abstract: Cytogenetic monitoring was carried out on a group of children from Gomel (Belarus), one of the areas most severely affected by radioactive contamination following the accident at the Chernobyl nuclear power plant, in 1986. We performed the micronucleus test (MN) in binucleated lymphocytes of 42 children (mean age: 11±2.34 years), 16 of whom were affected by thyroid gland tumor. Thirty healthy children living in Pisa (mean age: 14.96±2.17 years) were enrolled in the study as controls….
URL: http://www.sciencedirect.com/science/article/pii/S1383571899000121
Title: Dose response for T-cell receptor (TCR) mutants in patients repeatedly treated with 131 I for thyroid cancer
Author: Vershenya, Stanislav / Biko, Johannes / Drozd, Valentina / Lorenz, Reinhard / Reiners, Christoph / Hempel, Klaus
Reference: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 548 (1-2), p.27-33, Apr 2004
doi: 10.1016/j.mrfmmm.2003.12.015
Keywords: T-cell receptor; Mutation; Radiation; Thyroid cancer; Chernobyl
Abstract: The T-cell receptor mutant frequency (TCR-Mf) was measured in 53 young adults, who were treated with radioiodine for thyroid cancer. Patients came from the southern part of Belarus. This region had suffered the most from the Chernobyl Disaster. TCR-Mf was determined by flow cytometry before and after 1 to maximal 10 treatments. Before treatment, TCR-Mf of patients was 2.0×10−4. This Mf value is in the same range as that of young healthy students. After radioiodine therapy (RIT), TCR-Mf increases within about half a year to a maximum…
URL: http://www.sciencedirect.com/science/article/pii/S0027510704000223
Author: Moses, Willieford / Weng, Julie / Khanafshar, Elham / Duh, Quan-Yang / Clark, Orlo H. / Kebebew, Electron
Reference: Journal of Surgical Research, 160 (2), p.179-183, May 2010
doi: 10.1016/j.jss.2009.05.031
Keywords: thyroid cancer; somatic mutations; gender; age; outcome
Abstract: …rearrangement in papillary thyroid cancer and younger age was…exposure, such as the Chernobyl reactor meltdown…the incidence of thyroid cancer after the Chernobyl exposure was highest…younger patient’s thyroid gland is more susceptible…
URL: http://www.sciencedirect.com/science/article/pii/S002248040900287X
Title: Molecular Markers in Thyroid Cancer Diagnostics
Author: Kato, Meredith A. / Fahey, Thomas J., III
Reference: Surgical Clinics of North America, 89 (5), p.1139-1155, Oct 2009
doi: 10.1016/j.suc.2009.06.012
Keywords: Thyroid cancer diagnostics; Thyroid FNA; Thyroid cancer; Galectin-3; HBME-1; Microarray
Abstract: …Approximately 37,340 cases of thyroid cancer were projected for 2008…with differentiated thyroid cancer is the RET/PTC rearrangement…in c-cells of the thyroid, it is not highly expressed…induced PTC. Among post-Chernobyl children with PTC…
URL: http://www.sciencedirect.com/science/article/pii/S003961090900084X
Title: Surgical Management of Well-Differentiated Thyroid Cancer: State of the Art
Author: Suliburk, James / Delbridge, Leigh
Reference: Surgical Clinics of North America, 89 (5), p.1171-1191, Oct 2009
doi: 10.1016/j.suc.2009.06.013
Keywords: Thyroid cancer; Lymph nodes; Thyroidectomy ; Papillary; Follicular
Abstract: …of the post-Chernobyl childhood-induced papillary thyroid carcinomas. 25…radiation-induced cancer. These mutations…and the National Cancer Institute (NCI) ( www.cancer.gov ). 2 Prior…guidelines/thyroid_carcinoma…
URL: http://www.sciencedirect.com/science/article/pii/S0039610909000851
Author: Igumnov, S.A. / Drozdovitch, V.V.
Reference: European Psychiatry, 13 (Supplement 4), p.313s, Jan 1998
doi: 10.1016/S0924-9338(99)80644-0
Keywords:
Abstract: …DEVELOPMENT OF CHILDREN WITH THYROID CANCER EXPOSED FOLLOWING THE CHERNOBYL ACCIDENT (CLINICAL AND DOSIMETRY…children at the age 10-15 with thyroid cancer exposed following the Chemobyl…investigation the individual thyroid doses from 131 1have been…
URL:http://www.sciencedirect.com/science/article/pii/S0924933899806440
Title: Radiation hazards in children – Lessons from Chernobyl, Three Mile Island and Fukushima
Author: Fushiki, Shinji
Reference: Brain and Development, 35 (3), p.220-227, Mar 2013
doi: 10.1016/j.braindev.2012.09.004
Keywords: Ionizing radiation; Health effects; Children; Developing brain; Nuclear power plant accident
Abstract: On March 11, 2011, Japan was hit by the Great East Japan Earthquake followed by the Fukushima Daiichi Nuclear Disaster. Firstly, this review focuses on what happened after the accidents at the Three Mile Island nuclear power station in 1979 and the Chernobyl nuclear power plant in 1986, in terms of the effects of these incidents on health. The most critical issue when considering the effects of radiation on the health of children was the increase of thyroid cancer, as clearly demonstrated among people who were children or adolescence at the time of the Chernobyl accident….
URL:http://www.sciencedirect.com/science/article/pii/S0387760412002264
Author: Igumnov, S.A. / Drozdovitch, V.V
Reference: European Psychiatry, 13 (Supplement 4), p.313s, Jan 1998
doi: 10.1016/S0924-9338(99)80644-0
Keywords:
Abstract: …DEVELOPMENT OF CHILDREN WITH THYROID CANCER EXPOSED FOLLOWING THE CHERNOBYL ACCIDENT (CLINICAL AND DOSIMETRY…children at the age 10-15 with thyroid cancer exposed following the Chemobyl…investigation the individual thyroid doses from 131 1have been…
URL: http://www.sciencedirect.com/science/article/pii/S0924933899806440
Author: Nakashima, Masahiro / Takamura, Noboru / Namba, Hiroyuki / Saenko, Vladimir A. / Suzuki, Keiji / Meirmanov, Serik / Hayashi, Tomayoshi / Sekine, Ichiro
Reference: International Congress Series, 1299, p.251-255, Feb 2007
doi: 10.1016/j.ics.2006.09.002
Keywords: Thyroid cancer; RET oncogene; Genomic instability; 53BP1; Radiation; Interphase FISH
Abstract: RET oncogene rearrangement is a well-known molecular alteration observed in papillary thyroid cancer (PTC). RET rearrangement is the commonest oncogenic alterations in Chernobyl-related PTC; nearly all to RET/PTC1 or RET/PTC3, resulting from paracentric inversion of chromosome 10. Other less common variants, usually forming as a result of interchromosomal translocation, occur in an extremely limited number of cases….
URL:http://www.sciencedirect.com/science/article/pii/S0531513106006182