High frequency and allele-specific differences of BRCA1 founder mutations in breast cancer and ovarian cancer patients from Belarus.

Title: High frequency and allele-specific differences of BRCA1 founder mutations in breast cancer and ovarian cancer patients from Belarus.

Author: Bogdanova NV, Antonenkova NN, Rogov YI, Karstens JH, Hillemanns P, Dörk T.

Reference: Clinical Genetics Volume 78, Issue 4, pages 364–372, October 2010

DOI: 10.1111/j.1399-0004.2010.01473.x

Keywords: BRCA1, breast cancer, founder mutations, genetic susceptibility, ovarian cancer, radiation, Belarus

Abstract: Breast cancer and ovarian cancer are common malignancies in Belarus accounting for about 3500 and 800 new cases per year, respectively. For breast cancer, the rates and age of onset appear to vary significantly in regions differentially affected by the Chernobyl accident.

URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1399-0004.2010.01473.x/abstract

キーワードタグ

前後へのリンク