Post-radiation encephalopathy: experimental studies and clinical observations
Redactor: A.P. Romodanov
Reference: Київ: УНДІНХ АМН України, 1993
Keywords: brain, Central nervous System
タグ「Ionizing radiation」
Discussions about the role of ionizing radiation and stress in the genesis of neuropsychiatric consequences of the Chernobyl disaster
Author: K.M. Loganovsky
Reference: Журнал АМН України. (Journal of AMS of Ukraine), 2006
・For detailed information on the article contact the National Scientific Center for Radiation Medicine of Ukraine. The center’s home page is: http://www.national.rcrm.net.ua/index.php/en/
Whether low doses of ionizing radiation affect the human brain?
Author: K.N. Loganovsky
Reference: Український медичний часопис (Ukrainian Medical Magazine), 2009
Keywords: ionizing radiation, low doses, Chernobyl accident, brain, radiosensitivity, radiocerebral effects, exposure in utero.
Abstract: The aim is to analyze the current evidences on radiocerebral effects following exposure to 20 mSv on fetus and >300 mSv on thyroid in utero; 16–25 weeks — >10 mSv and >200 mSv, respectively. A life span study should be done for the cohort of prenatally irradiated persons as a result of the Chernobyl accident,as well as those exposed at the age of 0–1 years. These survivors are under increased risk of different neuropsychiatric disorders, including schizophrenia. Radiation exposure in childhood is obviously associated with dose-related cognitive decline in adulthood and neuropsychiatric disorders, including schizophrenia, later in life. The possible dose thresholds of delayed radiation brain damage are the doses as low as 0.1–1.3 Gy on the brain in childhood. In adults, the radiation-associated cerebrovascular effects were obtained at >0.15–0.25 Sv. Dose-related neuropsychiatric, neurophysiological, neuropsychological, and neuroimaging abnormalities following exposure to >0.3 Sv, neurophysiological and neuroimaging radiation markers at doses >1 Sv were revealed. Postradiation brain damage is predominantly localized in the frontal-temporal areas of the left hemisphere and involves both white and gray matter of the brain. The cerebral structural and functional abnormalities after irradiation are characteristic as frontal and temporal cortex atrophy, changes of subcortical structures and neuronal pathways, mainly in the dominant hemisphere. Adulthood radiation exposure is the risk factor for the Chronic Fatigue Syndrome as the predisposition for neurodegeneration, cognitive deficit and other neuropsychiatric disorders development, accelerating CNS ageing, as well as the new model of schizophrenia. Studies on radiation neuropsychiatric effects should be realized.
URL: http://www.umj.com.ua/wp-content/uploads/archive/71/pdf/1440_rus.pdf?upload
Effect of ionizing radiation on the nervous system
Author: A.V. Lebedinsky, Z.N. Nakhilnitskaya
Reference: Атомиздать (Atom publishing), 1960
Keywords: dose-dependent effect, nervous system, X-ray exposure, EEG
Chronic cerebrovascular pathology in the chernobyl accident consequences liquidators, in remote period after radiation exposure
Author: N.V. Denisyuk
Reference: Український медичний часопис (Ukrainian Medical Magazine), 2006
Keywords: ionizing radiation, Chernobyl accident, ultrasonic Dopplerography, cerebrovascular pathology
Abstract: Clinical-angioneurological peculiarities of chronic cerebrovascular pathology in remote period after radiation exposure to doses ranged from 0.025 to 3.5 Sv were determined on the basis of comprehensive clinical and neurophysiological investigations, as well as qualitative and quantitative estimation of the ultrasonic Dopplerography parameters in 100 men exposed to ionizing radiation as a result of the Chernobyl accident (liquidators; main group), 135 patients with cerebrovascular pathology (comparison group) and 63 healthy men (control group). A target artery (left internal carotid artery/ICA) and the dopplerographic marker of the radiation brain injury in dose range 0.3–3.5 Sv (reduction of the systolic circulation in the left ACI) were revealed. Disturbances of the cerebral hemodynamics in remote period after radiation exposure are etiologically heterogenous; along with general risk factors (age, alcohol abuse, tobacco smoking, somatic pathology) a role of radiation factor was determined at doses exceeded 0.3 Sv. A dose–effect relationship was revealed towards the reduction of the systolic circulation in the left ICA in liquidators irradiated by 0.3–3.5 Sv and without bad habits and liver pathology.
Reaction of the nervous system to harmful ionizing radiation
Author: A.K. Guskova, I.N. Shakirova
Reference: Журн. невропатол. и психиатр. им. С.С. Корсакова. (journal of neuropathology and psychiatry named after S.S. Korsakov), 1989
URL: http://www.kgmu.kcn.ru:8888/cgi-bin/irbis64r_01/cgiirbis_64.exe
The combined effect of ionizing radiation and other environmental factors on living organisms; new patterns and perspectives
Title: The combined effect of ionizing radiation and other environmental factors on living organisms; new patterns and perspectives
Author: Komarova, Ludmila Nikolayevna
Reference: Obninsk, 2009
Keywords: radiobiology, ionizing radiation, living organisms, synergic interaction
Abstract: The aim of this work is the theoretical study and experimental verification of the mechanism of the ionizing radiation interaction with the physical and chemical agents of the environment for the development of a new concept of synergic interaction and prediction of biological effects when combined exposures.
WHO: Risk of cancer disease among inhabitants of Fukushima is law.
Reference: RIA news, 28. November, 2012
Keywords: Fukushima, harmful fallouts, biological consequences of ion exposure
Abstract: WHO reports that thyroid cancer incident among adolescence and adults, living in vicinity of Fukushima Daiichi NPP, should be extremely law. If the incidence among people living in areas without radioactive contamination is 0.76% for female and 0.21% for masculine, the same for the ones living in contaminated areas is 0.85% for female and 0.23 for masculine. This is the first of such estimation reported by WHO, and it is based on data from the disasters in Nagasaki and Hiroshima.
Combined biological effect of ionizing radiation and other hazardous environment factors (scientific review)
Author: Petin V.G., Dergacheva I.P., Zhurakovskaya G.P.
Reference: Bulletin “РАДИАЦИЯ И РИСК” (Radiation and risk), 2001
ISSN: 0131-3878
Keywords: ionizing radiation, hazardous factors, combined effect environment
Abstract: The Chernobyl accident and other radiation-related accidents are characterized by involvement of a variety of hazardous factors which aggravate the damaging action of ionizing radiation. The synergetic effect of different agents can exacerbate anticipated consequences of an accident. This review attempts to establish regularities in biological responses to the combined effect of ionizing radiation and other hazardous environmental factors of chemical, biological or physical nature. A series of universal features accounting for responses of different cell-systems, animals and people have been identified. These features do not depend on the nature of an agent used in conjunction with ionizing radiation or test-system and biological object under study. A conclusion is made regarding a possible significance of the synergetic effect resulting from interaction of various agents for enhancing consequences of the Chernobyl accident.
Rural areas affected by the Chernobyl accident: Radiation exposure and remediation strategies
Title: Rural areas affected by the Chernobyl accident: Radiation exposure and remediation strategies
Author: P. Jacob, S. Fesenko, I. Bogdevitch, V. Kashparov, N. Sanzharova, N. Grebenshikova, N. Isamov, N. Lazarev, A. Panov, A. Ulanovsky, Y. Zhuchenko, M. Zhurba
Reference: Science of The Total Environment, Volume 408, Issue 1, 15 December 2009, Pages 14-25
DOI: http://dx.doi.org/10.1016/j.scitotenv.2009.09.006
Keywords: Caesium; Chernobyl; Ionizing radiation; Rehabilitation; Remediation
Abstract: Main objectives of the present work were to develop an internationally agreed methodology for deriving optimized remediation strategies in rural areas that are still affected by the Chernobyl accident, and to give an overview of the radiological situation in the three affected countries, Belarus, Russia and Ukraine. Study settlements were defined by having in 2004 less than 10,000 inhabitants and official dose estimates exceeding 1 mSv. Data on population, current farming practices, contamination of soils and foodstuffs, and remedial actions previously applied were collected for each of such 541 study settlements. Calculations of the annual effective dose from internal radiation were validated with extensive data sets on whole body counter measurements. According to our calculations for 2004, in 290 of the study settlements the effective dose exceeded 1 mSv, and the collective dose in these settlements amounted to about 66 person-Sv. Six remedial actions were considered: radical improvement of grassland, application of ferrocyn to cows, feeding pigs with uncontaminated fodder before slaughter, application of mineral fertilizers for potato fields, information campaign on contaminated forest produce, and replacement of contaminated soil in populated areas by uncontaminated soil.
URL: http://www.sciencedirect.com/science/article/pii/S004896970900850X