タグ「Pregnancy」
Title: Chernobyl fallout and outcome of pregnancy in Finland
Author: A Auvinen, M Vahteristo, H Arvela, M Suomela, T Rahola, M Hakama, and T Rytömaa
Reference: Environ Health Perspect. 2001 February; 109(2): 179–185.
Keywords: Finland, pregnancy
Abstract: Possible effects of Chernobyl fallout on outcome of pregnancy in Finland were evaluated in a nationwide follow-up study. The outcomes were the rate of live births and stillbirths, pregnancy loss, and induced abortions by municipality. Exposure was assessed based on nationwide surveys of radiation dose rate from the Chernobyl fallout, from both external and internal exposures. Using these measurements, we estimated the monthly dose rate for each of the 455 Finnish municipalities. On average, the dose rate from Chernobyl fallout reached 50 microSv per month in May 1986–a doubling of the natural background radiation. In the most heavily affected area, 4 times the normal background dose rates were recorded. Given the underlying regional differences in live birth, stillbirth, and abortion rates, we used longitudinal analysis comparing changes over time within municipalities. A temporary decline in the live birth rate had already begun before 1986, with no clear relationship to the level of fallout. A statistically significant increase in spontaneous abortions with dose of radiation was observed. No marked changes in induced abortions or stillbirths were observed. The decrease in the live birth rate is probably not a biological effect of radiation, but more likely related to public concerns of the fallout. The effect on spontaneous abortions should be interpreted with caution, because of potential bias or confounding. Further, there is little support in the epidemiologic literature on effects of very low doses of radiation on pregnancy outcome.
URL:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240640/
Title: Fear of the unknown: ionizing radiation exposure during pregnancy
Author: Reinou S. Groen, Jin Y. Bae, Kyoung J. Lim
Reference: American Journal of Obstetrics and Gynecology, Volume 206, Issue 6, June 2012, Pages 456-462
DOI: http://dx.doi.org/10.1016/j.ajog.2011.12.001
Keywords: lactation, nuclear, pregnancy, protective measures, radiation, Fukushima
Abstract: Ionizing radiation during pregnancy can negatively impact a fetus. In light of the Fukushima nuclear plant disaster in Japan, we discuss existing knowledge on the health effects of radiation and preventive measures for pregnant women. Overall, the risk of exposure to radiation is limited but severe defects can result from fetal radiation exposure >100 mGy equivalent to 10 rad (>1000 chest x-rays). While such high-level exposure rarely occurs during single medical diagnostic procedures, caution should be exercised for pregnant women. As a protective public health measure in light of a disaster, evacuation, shielding, and elimination of ingested radioactive isotopes should all be considered. Detailed radiation reports with health effects and precautionary measures should be available for a population exposed to more than background radiation.
URL: http://www.sciencedirect.com/science/article/pii/S0002937811023520
Title: Pregnancy outcome in Norway after Chernobyl
Author: LM Irgens, RT Lie, M Ulstein, T Skeie Jensen, R Skjærven, F Sivertsen, JB Reitan, F Strand, T Strand, F Egil Skjeldestad
Reference: Biomedicine & Pharmacotherapy, Volume 45, Issue 6, 1991, Pages 233-241
DOI: http://dx.doi.org/10.1016/0753-3322(91)90023-M
Keywords: Pregnancy outcome, Chernobyl, Norway
Abstract: Pregnancy outcome has been studied in terms of legal abortions, early spontaneous abortions and total number of pregnancies (in an ad hoc study covering 6 counties) as well as various perinatal health problems (on the basis of routinely recorded data for epidemiological surveillance from the Medical Birth Registry of Norway). Apparently, no effects were observed in terms of an increased occurrence of legal abortions, while spontaneous abortions increased from 2.4% of all pregnancies during the last 12 months before the accident to 3% after the accident. At the same time, the total number of pregnancies somewhat decreased. Based on monthly measurements in each municipality of external and internal (food-based) doses, dose-response associations were assessed for a number of perinatal health problems. No associations were observed.
URL: http://www.sciencedirect.com/science/article/pii/075333229190023M
Title: Well-differentiated carcinoma of the thyroid
Author: Boone, Ryan T / Fan, Chun-Yang / Hanna, Ehab Y
Reference: Otolaryngologic Clinics of North America, 36 (1), p.73-90, Feb 2003
doi: 10.1016/S0030-6665(02)00127-5
Keywords: Fine needle aspiration biopsy, Staging, Pathology, Papillary carcinoma, Follicular carcinoma, Hurthle cell carcinoma, Treatment, Thyroidectomy, Neck dissection, Adjuvant treatment, Prognosis, Special considerations, Cancer of the thyroid in children, Cancer of the thyroid during pregnancy
Abstract: …family history of thyroid disease or cancer is important in…underlying undiagnosed thyroid disease. A nodule…aftermath of the Chernobyl nuclear accident…duration of the thyroid mass and any associated…patients with thyroid cancer as they usually…
URL: http://www.sciencedirect.com/science/article/pii/S0030666502001275
Title: High-dose radioiodine treatment for differentiated thyroid carcinoma is not associated with change in female fertility or any genetic risk to the offspring
Author: Bal, Chandrasekhar / Kumar, Ajay / Tripathi, Madhavi / Chandrashekar, Narayana / Phom, Hentok / Murali, Nadig R. / Chandra, Prem / Pant, Gauri S.
Reference: International Journal of Radiation Oncology*Biology*Physics, 63 (2), p.449-455, Oct 2005
doi: 10.1016/j.ijrobp.2005.02.043
Keywords: Differentiated thyroid cancer; Radioiodine; Pregnancy; Female fertility; Genetic risk
Abstract: ..e., no evidence of cancer) in 3 cases (43…diagnosis and treatment of thyroid cancer. Three cases of spontaneous…for the evaluation of thyroid remnants, ablation of…carcinogenic effects after the Chernobyl nuclear reactor accident…
URL: http://www.sciencedirect.com/science/article/pii/S0360301605004049
Title: Thyroid Disorders in Pregnancy
Author: Krajewski, Dorota A. / Burman, Kenneth D.
Reference: Endocrinology and Metabolism Clinics of North America, 40 (4), p.739-763, Dec 2011
doi: 10.1016/j.ecl.2011.08.004
Keywords: Pregnancy; Thyroid dysfunction; Maternal hypothyroidism; Gestational thyrotoxicosis; Graves’ disease; Postpartum thyroiditisПослеродовой тиреоидит; Fetal neurodevelopment; Thyroid cancer
Abstract: …iodine-131 for treatment of thyroid cancer. Note small uptake in the thyroid…treatment of Graves’ disease and thyroid cancer in undiagnosed pregnancy. Can…week, 2 women with a history of thyroid cancer needed a further increase in levothyroxine…
URL: http://www.sciencedirect.com/science/article/pii/S0889852911000697
