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カテゴリー「thyroid cancer」

What Have We Learnt From Chernobyl? What Have We Still To Learn?

Title: What Have We Learnt From Chernobyl? What Have We Still To Learn?

Author: Thomas, G.A. / Tronko, M.D. / Tsyb, A.F. / Tuttle, R.M.

Reference: Clinical Oncology, 23 (4), p.229-233, May 2011

doi: 10.1016/j.clon.2011.02.001

Abstract: …rearrangement in post-Chernobyl thyroid cancer, suggesting that some…gene (PTC3) in post-Chernobyl papillary thyroid cancer may reflect the association…Clinical Outcome of Post-Chernobyl Thyroid Cancer Different from that of…

URL: http://www.sciencedirect.com/science/article/pii/S0936655511005449

The Chernobyl Accident — An Epidemiological Perspective

Title: The Chernobyl Accident — An Epidemiological Perspective

Author: Cardis, E. / Hatch, M.

Reference: Clinical Oncology, 23 (4), p.251-260, May 2011

doi: 10.1016/j.clon.2011.01.510

Keywords: Cancer; cataracts; cardiovascular diseases; Chernobyl accident; radiation; thyroid cancer

Abstract: Twenty-five years have passed since radioactive releases from the Chernobyl nuclear accident led to the exposure of millions of people in Europe. Studies of affected populations have provided important new data on the links between radiation and cancer—particularly the risk of thyroid tumours from exposure to iodine isotopes—that are important not only for a fuller scientific understanding of radiation effects, but also for radiation protection. It is now well documented that children and adolescents exposed to radioiodines from Chernobyl fallout have a sizeable dose-related increase in thyroid cancer, with the risk greatest in those youngest at exposure and with a suggestion that deficiency in stable iodine may increase the risk….

URL: http://www.sciencedirect.com/science/article/pii/S0936655511005425

165 Present Status of Childhood Thyroid Carcinoma in Belarus…

Title: 165 Present Status of Childhood Thyroid Carcinoma in Belarus…

Author: Akira SUGENOYA, Yuri E. DEMIDCHIK, Evgeny P. DEMIDCHIK

Reference: [PDF-65K]Oct 2002  Belarus National Thyroid Cancer Canter

Abstract: …related to the Chernobyl accident was only thyroid cancer in children for…Belarus after Chernobyl The number of patients with thyroid cancer in both children…et.al., Thyroid Cancer after Chernobyl, Nature 359…

URL: http://www.rri.kyoto-u.ac.jp/NSRG/reports/kr21/kr21pdf/Sugenoya.pdf

Summary of the cytological diagnosis of childhood thyroid diseases around Chernobyl

Title: Summary of the cytological diagnosis of childhood thyroid diseases around Chernobyl

Author: Ito, Masahiro / Yamashita, Shunichi
Reference: International Congress Series, 1234, p.185-192, May 2002

doi: 10.1016/S0531-5131(01)00607-0

Keywords: Thyroid cancer; Cytology; Childhood; Fine-needle aspiration biopsy

Abstract: A combination of ultrasonography and fine-needle aspiration biopsy was performed in the screening project on children around Chernobyl. The aspirated materials from 446 cases were analyzed cytologically. The ultrasonographical screening revealed a 2.9% prevalence of thyroid abnormalities. Fine-needle aspiration biopsy (FNA), conducted in 446 cases, revealed the following diseases: papillary carcinoma, 7.2%; follicular neoplasm, 10.3%; adenomatous goiter, 22.4%; chronic thyroiditis, 26.2%; and cyst, 22.9%….

URL:http://www.sciencedirect.com/science/article/pii/S0531513101006070

Validation of 131 I ecological transfer models and thyroid dose assessments using Chernobyl fallout data from the Plavsk district, Russia

Title: Validation of 131 I ecological transfer models and thyroid dose assessments using Chernobyl fallout data from the Plavsk district, Russia

Author: Zvonova, I. / Krajewski, P. / Berkovsky, V. / Ammann, M. / Duffa, C. / Filistovic, V. / Homma, T. / (…) / Webbe-Wood, D.
Reference: Journal of Environmental Radioactivity, 101 (1), p.8-15, Jan 2010

doi: 10.1016/j.jenvrad.2009.08.005

Keywords: Chernobyl accident; Iodine-131; Environment modeling; Models validation; Population; Thyroid dose

Abstract: Within the project “Environmental Modelling for Radiation Safety” (EMRAS) organized by the IAEA in 2003 experimental data of 131I measurements following the Chernobyl accident in the Plavsk district of Tula region, Russia were used to validate the calculations of some radioecological transfer models. Nine models participated in the inter-comparison. Levels of 137Cs soil contamination in all the settlements and 131I/137Cs isotopic ratios in the depositions in some locations were used as the main input information. 370 measurements of 131I content in thyroid of townspeople and villagers, and 90 measurements of 131I concentration in milk were used for validation of the model predictions….

URL:http://www.sciencedirect.com/science/article/pii/S0265931X09001751

Risk of radiogenic malignant and benign thyroid diseases for the population of the Oryol oblast after the Chernobyl accident: outcome of large-scale epidemiological studies

Title: Risk of radiogenic malignant and benign thyroid diseases for the population of the Oryol oblast after the Chernobyl accident: outcome of large-scale epidemiological studies

Author: Ivanov, Victor K / Tsyb, Anatoly F / Chekin, Sergey Yu / Parshin, Vladimir S / Maksioutov, Marat A / Saenko, Alexander S / Sevankaev, Alexander V / (…) / Vlasov, Oleg K
doi: 10.1016/S0531-5131(03)01144-0

Keywords: Oryol oblast; Chernobyl accident; Thyroid dose; Radiation risk

Abstract: Due to the Chernobyl accident, the following four oblasts of the Russian Federation—Bryansk, Oryol, Tula and Kaluga—were contaminated with radionuclides at the utmost. In the paper, the problem of the assessment of risk for the development of radiogenic malignant and benign thyroid diseases among the population of the Oryol oblast is discussed. Mean thyroid dose to the residents of the Oryol oblast was 46.3 mGy for children and 10.9 mGy for adults….

URL: http://www.sciencedirect.com/science/article/pii/S0531513103011440

Chernobyl-related ionising radiation exposure and cancer risk: an epidemiological review

Title: Chernobyl-related ionising radiation exposure and cancer risk: an epidemiological review

Author: Moysich, Kirsten B / Menezes, Ravi J / Michalek, Arthur M

Reference: The Lancet Oncology, 3 (5), p.269-279, May 2002

doi: 10.1016/S1470-2045(02)00727-1

Abstract: The Chernobyl nuclear accident on 26th April, 1986, led to a massive release of radionuclides into the environment. Although vast areas of Europe were affected by Chernobyl-related ionising radiation, the accident had the greatest impact in Belarus, Ukraine, and the Russian Federation. Epidemiological studies that have investigated the link between the Chernobyl accident and cancer have largely focused on malignant diseases in children, specifically thyroid cancer and leukaemia….

URL: http://www.sciencedirect.com/science/article/pii/S1470204502007271

Treatment of Thyroid Cancer: 2007—A Basic Review

Title: Treatment of Thyroid Cancer: 2007—A Basic Review

Author: Randolph, Gregory W. / Thompson, Geoffrey B. / Branovan, Daniel Igor / Tuttle, R. Michael

Reference: International Journal of Radiation Oncology*Biology*Physics, 69 (2 Supplement), p.S92-S97, Oct 2007

doi: 10.1016/j.ijrobp.2007.06.027

Abstract: …development of thyroid cancer using lessons…experiences in Chernobyl. Finally, Dr…follow-up for thyroid cancer, including suppression…the Lessons of Chernobyl Surgical treatment…well-differentiated thyroid cancer has evolved over…

URL:http://www.sciencedirect.com/science/article/pii/S0360301607010346

Thyroid diseases around Chernobyl: from autoimmune diseases to malignant tumors

 

Title: Thyroid diseases around Chernobyl: from autoimmune diseases to malignant tumors

Author: Pacini, Furio / Agate, Laura / Molinaro, E. / Elisei, Rossella / Pinchera, Aldo
Reference: International Congress Series, 1234, p.175-183, May 2002

doi: 10.1016/S0531-5131(01)00606-9

Keywords: Thyroid cancer; Radiation; Chernobyl; Autoimmune disease

Abstract: Both an increased incidence of thyroid carcinoma mainly of the papillary histotype and to a lesser extent, of autoimmune phenomena have been observed, several years after external irradiation to the head and the neck, in subjects treated for various non-thyroidal disorders, in atomic bomb survivors in Japan, and in residents of the Marshall Island exposed to radiation during the testing of hydrogen bombs. More recently, the exposure to radioactive fallout as a result of the Chernobyl nuclear reactor accident has clearly confirmed the causal association of radiation exposure and the development of thyroid autoimmune phenomena in the population exposed to radiation.This article will review the most significant features of thyroid diseases associated with the post-Chernobyl radioactive contamination.

URL: http://www.sciencedirect.com/science/article/pii/S0531513101006069

Studies of cancer risk among Chernobyl liquidators: materials and methods

Title: Studies of cancer risk among Chernobyl liquidators: materials and methods

Author: A Kesminiene / E Cardis / V Tenet / V K Ivanov / J Kurtinaitis / I Malakhova / A Stengrevics / M Tekkel

Reference: Journal of Radiological Protection, 22 (3A), p.A137-A141, Sep 2002

doi: 10.1088/0952-4746/22/3A/324

Abstract: The current paper presents the methods and design of two case–control studies among Chernobyl liquidators—one of leukaemia and non-Hodgkin lymphoma, the other of thyroid cancer risk—carried out in Belarus, Estonia, Latvia, Lithuania and Russia. The specific objective of these studies is to estimate the radiation induced risk of these diseases among liquidators of the Chernobyl accident, and, in particular, to study the effect of exposure protraction and radiation type on the risk of radiation induced cancer in the low-to-medium- (0–500 mSv) radiation dose range….

URL: http://iopscience.iop.org/0952-4746/22/3A/324/

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