Title: Treatment of Thyroid Cancer: 2007—A Basic Review
Author: Randolph, Gregory W. / Thompson, Geoffrey B. / Branovan, Daniel Igor / Tuttle, R. Michael
Reference: International Journal of Radiation Oncology*Biology*Physics, 69 (2 Supplement), p.S92-S97, Oct 2007
doi: 10.1016/j.ijrobp.2007.06.027
Abstract: …development of thyroid cancer using lessons…experiences in Chernobyl. Finally, Dr…follow-up for thyroid cancer, including suppression…the Lessons of Chernobyl Surgical treatment…well-differentiated thyroid cancer has evolved over…
URL:http://www.sciencedirect.com/science/article/pii/S0360301607010346
Title: Thyroid diseases around Chernobyl: from autoimmune diseases to malignant tumors
Author: Pacini, Furio / Agate, Laura / Molinaro, E. / Elisei, Rossella / Pinchera, Aldo
Reference: International Congress Series, 1234, p.175-183, May 2002
doi: 10.1016/S0531-5131(01)00606-9
Keywords: Thyroid cancer; Radiation; Chernobyl; Autoimmune disease
Abstract: Both an increased incidence of thyroid carcinoma mainly of the papillary histotype and to a lesser extent, of autoimmune phenomena have been observed, several years after external irradiation to the head and the neck, in subjects treated for various non-thyroidal disorders, in atomic bomb survivors in Japan, and in residents of the Marshall Island exposed to radiation during the testing of hydrogen bombs. More recently, the exposure to radioactive fallout as a result of the Chernobyl nuclear reactor accident has clearly confirmed the causal association of radiation exposure and the development of thyroid autoimmune phenomena in the population exposed to radiation.This article will review the most significant features of thyroid diseases associated with the post-Chernobyl radioactive contamination.
URL: http://www.sciencedirect.com/science/article/pii/S0531513101006069
Title: Studies of cancer risk among Chernobyl liquidators: materials and methods
Author: A Kesminiene / E Cardis / V Tenet / V K Ivanov / J Kurtinaitis / I Malakhova / A Stengrevics / M Tekkel
Reference: Journal of Radiological Protection, 22 (3A), p.A137-A141, Sep 2002
doi: 10.1088/0952-4746/22/3A/324
Abstract: The current paper presents the methods and design of two case–control studies among Chernobyl liquidators—one of leukaemia and non-Hodgkin lymphoma, the other of thyroid cancer risk—carried out in Belarus, Estonia, Latvia, Lithuania and Russia. The specific objective of these studies is to estimate the radiation induced risk of these diseases among liquidators of the Chernobyl accident, and, in particular, to study the effect of exposure protraction and radiation type on the risk of radiation induced cancer in the low-to-medium- (0–500 mSv) radiation dose range….
URL: http://iopscience.iop.org/0952-4746/22/3A/324/
Title: Ret proto-oncogene rearrangement in thyroid cancer around Semipalatinsk nuclear testing site
Author: Alipov, Gabit / Ito, Masahiro / Prouglo, Yuriy / Takamura, Noboru / Yamashita, Shunichi
Reference: The Lancet, 354 (9189), p.1528-1529, Oct 1999
doi: 10.1016/S0140-6736(99)03548-5
Abstract: …such molecular analysis on thyroid cancer tissue samples, to add to other data on excess cancer incidence. 3 After the Chernobyl nuclear plant accident, a…especially ret/PTC3 in thyroid cancer tissues—has been found…
URL: http://www.sciencedirect.com/science/article/pii/S0140673699035485
Title: The alkaline single-cell gel electrophoresis (SCGE) assay applied to the analysis of radiation-induced DNA damage in thyroid cancer patients treated with 131 I
Author: Gutiérrez, Sara / Carbonell, Elisabet / Galofré, Pere / Creus, Amadeu / Marcos, Ricardo
Reference: Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 413 (2), p.111-119, Mar 1998
doi: 10.1016/S1383-5718(98)00010-2
Keywords: Human blood cell; Comet assay; Thyroid cancer patient; 131I sodium iodide
Abstract: …nodular goiter or with thyroid carcinoma, subjected…a liquidator in the Chernobyl area immediately after…investigation of the Chernobyl worker indicated…accumulation in the thyroid, this gland would…same group of thyroid cancer patients by using the…
URL: http://www.sciencedirect.com/science/article/pii/S1383571898000102
Title: Thyroid cancer after radiation exposure
Author: Rubino, C. / Cailleux, A.F. / De Vathaire, F. / Schlumberger, M.
Reference: European Journal of Cancer, 38 (5), p.645-647, Mar 2002
doi: 10.1016/S0959-8049(02)00009-6
Abstract: …consequence of the Chernobyl accident in 1986…km radius of Chernobyl: no thyroid cancer was observed in…related to the Chernobyl fallout, the…radiation dose to the thyroid gland being low…the thyroid cancer-related mortality…
URL: http://www.sciencedirect.com/science/article/pii/S0959804902000096
Title: Post Chernobyl NIS thyroid tissue, nucleic acid and data banks and integrated research
Author: Thomas, Geraldine A.
Reference: International Congress Series, 1234, p.127-134, May 2002
doi: 10.1016/S0531-5131(01)00603-3
Keywords: Chernobyl; Thyroid cancer; Tissue resource
Abstract: The increased incidence of thyroid carcinoma in patients, resident in the contaminated areas of Belarus, Ukraine and Russia and who were aged under 19 at the time of the Chernobyl accident has provided a unique opportunity for the scientific study of a human tumour of known radiation aetiology. It is important that not only the interests of the patients concerned come first, but also that information is not lost that may inform our response to a future accident, or could improve prognosis for those affected. We have therefore set up the first international cooperation—the Newly Independent States Chernobyl Tissue Bank (known by the acronym NISCTB)…
URL: http://www.sciencedirect.com/science/article/pii/S0531513101006033
Title: Long-term environment monitoring based on MTS-N (LiF:Mg, Ti) and MCP-N (LiF:Mg, Cu, P) thermoluminescent detectors
Author: Budzanowski, M.; Olko, P.; Obryk, B.; Ryba, E.; Nowak, A.
Reference: Radiation Measurements, Aug.-Dec. 2004, vol.38, no.4-6, pp. 821-4
doi: 10.1016/j.radmeas.2004.01.023
Keywords: Thermoluminescence; TLD; LiF; Environmental measurements
Abstract: An environmental radiation monitoring system using standard MTS-N (LiF:Mg, Ti) and high-sensitive thermoluminescent LiF:Mg,Cu,P (MCP-N) detectors was applied to control the radiation exposure over the area of the Institute of Nuclear Physics (INP) in Kraków. First environmental measurements using MTS-N detectors began in 1970 at five locations and were continued during the Chernobyl accident at six sites. In March 1987 high-sensitive MCP-N detectors read out in a manual TL reader were first introduced into service at the INP. Since 1992 about 60 locations over an area of the INP were selected for quarterly dose rate measurements, using an automatic TLD system based on MTS-N detectors placed in cards. In 2002 MTS-N detectors were replaced by high-sensitive MCP-N pellets.
URL: http://www.sciencedirect.com/science/article/pii/S1350448704000290
Title: Long-term investigations of radioactive matter in the air of Zagreb, Croatia
Author: Franic, Z.; Marovic, G.; Sencar, J.
Reference: Atmospheric Research, Sept. 2008, vol.89, no.4, pp. 391-5
doi: 10.1016/j.atmosres.2008.03.005
Keywords: Radioactivity; 137Cs; 7Be; Chernobyl accident; Effective dose
Abstract: Investigations on the distribution and fate of naturally occurring, nuclear-weapons-produced, and reactor-released radionuclides in the city of Zagreb, Coatia, have been conducted as part of the monitoring program for radioactive contamination of the human environment in Croatia since the early 1960s. This paper describes long-term investigations of man-made 137Cs and naturally occurring 7Be in the city of Zagreb after the Chernobyl accident. The Chernobyl nuclear accident caused a major increase in 137Cs activity concentrations only in 1986, which quickly decreased over the next few years to pre-Chernobyl values. The observed mean residence time for 137Cs in the air during the post-Chernobyl period from January 1987 to December 1990 was estimated to be 1.0 year. During this period, the observed mean residence time for 137Cs in fallout was estimated to be 0.9 years. The mean 7Be activity concentration in the air from 1987 to 2004 was (5.4 ± 2.8) × 10− 3 Bq m− 3. The measured 7Be activity concentrations showed seasonal behavior with the highest usually measured in July.
URL: http://www.sciencedirect.com/science/article/pii/S0169809508000689
Title: Testicular steroidogenesis is not altered by 137 cesium Chernobyl fallout, following in utero or post-natal chronic exposure.
Author: Grignard, Elise; Guéguen, Yann; Grison, Stéphane; Dublineau, Isabelle; Gourmelon, Patrick; Souidi, Maâmar.
Reference: Comptes Rendus Biologies. May2010, Vol. 333 Issue 5, p416-423. 8p.
doi: 10.1016/j.crvi.2010.02.003.
Keywords: TESTIS — Physiology; CESIUM — Isotopes; STEROID hormones — Synthesis; CHERNOBYL Nuclear Accident, Chornobyl, Ukraine, 1986; GENE expression; CONTAMINATION (Technology); RATS as laboratory animals
Abstract: The testis is especially sensitive to pollutants, including radionuclides. Following the Chernobyl nuclear power plant accident, several of these radionuclides were emitted and spread in the environment. Subsequently, children presented some disruptions of the endocrine system. To determine whether these disruptions were due to 137 cesium (137Cs) exposure, the effects of chronic contamination with low doses of 137Cs in utero or from birth on testicular steroidogenesis in rats were studied. Contamination was continued for 9 months. No modification was observed in circulating level of hormones (17β-estradiol, testosterone, follicle-stimulating hormone, luteinizing hormone) following in utero or post-natal contamination. Expression of several genes involved in testicular steroidogenesis was affected (cyp19a1, fxr, sf-1), without modification of protein expression or activity. Our results suggest that growing organisms may be affected at the molecular level by 137Cs contamination at this post-accidental dose.
URL: http://www.sciencedirect.com/science/article/pii/S1631069110000466
